An inquest is an investigation into the cause and circumstances of a death. Laws vary from state to state and the circumstances under which an inquest may be required are usually specified in a state’s statutes.

For example, if a person dies in a county with a medical examiner, the medical examiner (or authorized deputy) may be required to conduct an inquest under the these and other circumstances:

• when a person dies within 24 hours after being admitted to a hospital or institution, or dies in prison or jail;

• when a person is killed, or dies from an unnatural cause of death (unless executed by the state for a crime), or dies without one or more good witnesses;

• when the body or a body part of a person is found, and the cause or circumstances of death are unknown;

• when the circumstances of the death of any person lead to suspicion the person died by unlawful means;

• when any person commits suicide, or the circumstances of the person's death lead to suspicion the person committed suicide;

• when a person dies without having been attended by a duly licensed and practicing physician, and the local health officer or registrar required to report the cause of death does not know the cause of death;

• when the person is a child and the death is required to be reported by law; and

• when a person dies who has been attended immediately preceding death by a duly licensed and practicing physician or physicians, and such physician or physicians are not certain as to the cause of death and are unable to certify with certainty the cause of death.

In South Carolina, an inquest into the cause and circumstances of a death may be conducted under certain conditions as outlined by state statutes. These circumstances include deaths that occur within 24 hours of admission to a hospital or institution, deaths in prison or jail, deaths resulting from unnatural causes or without witnesses, found bodies with unknown causes of death, deaths under suspicious circumstances that may indicate unlawful means, suspected suicides, deaths without medical attendance where the cause is unknown to the reporting health officer, deaths of children that are legally mandated to be reported, and cases where attending physicians are uncertain about the cause of death. The responsibility to conduct an inquest typically falls on the county coroner or medical examiner, who is tasked with determining the cause and manner of death. The specific procedures and requirements for inquests in South Carolina are detailed in the state's Code of Laws, particularly in the sections pertaining to the powers and duties of coroners and medical examiners.